Inflammation plays a critical role in the development and progression of neurovascular disorders and stroke, impacting both acute and chronic phases of ...

Surely, inflammation is half a billion years old, since even the lowly starfish may experience it. Virtually every human being who ever lived has suffered from it, perhaps dozens or hundreds of times.

Background Interstitial fibrosis in lupus nephritis (LN) is often infiltrated by immune cells but typically regarded as ...

Single-cell analysis reveals fibroblast-mediated glycolysis drives systemic inflammation in dermatomyositis. Learn more about ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...

New findings identify CASP4/11 as detrimental to inflammation and coagulopathy associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Researchers recognize CASP4/11 as ...

Influenza A virus (IAV) infection during pregnancy causes severe maternal and perinatal complications, despite a lack of vertical transmission of IAV across the placenta. Here, we demonstrate a ...

Pharmacological activation of LANCL2 provides CNS immunometabolic support for the restoration of cognitive function markers in a mouse model of Alzheimer’s disease. Pharmacological activation of ...

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repetitive head impacts (RHI). However, individuals with similar RHI exposure have shown differing pathology, suggesting ...

Targeting and disabling a certain protein essential to transporting glucose properly through cells (Glucose Transporter 1, or ...