Leg pain, numbness, coldness, swelling, and skin changes, especially at night, can signal high LDL cholesterol. These ...

Medically reviewed by Christopher Lee, MD Key Takeaways Sitting or standing awkwardly for a long time can cause temporary numbness in your legs.Recurrent numbness can be a sign of a serious condition ...

High cholesterol often shows early effects in the legs because plaque can narrow the arteries that supply blood to the lower ...

Dear Mayo Clinic: I have been on medication to treat peripheral artery disease for nearly a year, but it doesn’t seem to help the numbness and cramping in my legs. Are stents always effective in ...

You don't need to call 999 if "you keep getting pain, numbness, swelling, or have difficulty moving a part of your body when ...

Diabetic neuropathy can cause pain or tingling in your legs, arms, hands, and feet. Topical and oral medications may provide some relief. Share on Pinterest Getty Images/Johner Images Diabetic ...

Leg weakness is not a typical sinus infection symptom. However, people may experience general fatigue or weakness. Leg weakness with a sinus infection may also be a sign of another underlying ...

Peripheral vascular disease is a lack of blood flow through the arteries, typically affecting the legs and feet. The main symptoms include pain, numbness, weakness in the legs and feet, skin ...

While peripheral artery disease symptoms are most common in upright positions, it’s possible for more severe cases to cause leg pain at night. The most commonly reported symptom of peripheral artery ...