Gastrointestinal stromal tumors (GISTs) represent a rare tumor entity that occurs in the muscular layer of the digestive tract. These tumors commonly metastasize to the liver and peritoneum, and ...

GIST originates in stromal tissue, differentiating it from epithelial-based GI cancers, and is classified as a sarcoma. Symptoms include fullness, fatigue, and GI bleeding, necessitating awareness and ...

GISTs originate from interstitial cells of Cajal and are staged by size, location, mitotic rate, and genetic mutations, influencing treatment strategies. Diagnosis involves imaging, endoscopy, biopsy, ...

Hoth Therapeutics Inc. has released preclinical findings demonstrating the efficacy of HT-KIT, a novel targeted therapy for gastrointestinal stromal tumors (GIST).

Immunohistochemical identification of SDHA-mutant gastrointestinal stromal tumors (GISTs). Neoadjuvant treatment of locally advanced GIST: Results of APOLLON, a prospective, open label phase II study ...

Gastrointestinal stromal tumors (GISTs) are a diverse group of tumors that account for about 80% of mesenchymal neoplasms in the gastrointestinal tract. Tyrosine kinase inhibitors (TKIs) against KIT ...

Kura Oncology, Inc. announced the initiation of the KOMET-015 Phase 1 clinical trial, which will evaluate the safety and effectiveness of ziftomenib, an investigational menin inhibitor, in combination ...

A little over two years after he had a Gastrointestinal Stromal Tumor (GIST) removed and he was deemed cancer-free, a beloved comedic actor revealed the disease has returned. Smosh star Keith Leak Jr.