Acetyl-CoA, as a central metabolic intermediate, is widely used in macromolecule biosynthesis and energy production to support cell growth and proliferation. As a donor of acetyl group, acetyl-CoA is ...

A study from Van Andel Institute reveals that immune cells use two pathways, ACLY and ACSS2, to produce acetyl-CoA, an essential metabolite for fighting infection and cancer. These findings highlight ...

By Dr. Sanchari Sinha Dutta, Ph.D. By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers ...

为探究巴豆酰辅酶 A（Crotonyl-CoA）在生物体内的代谢及功能，研究人员开展相关研究。发现 Crotonyl-CoA 存在于多种组织，ECHS1 和 CDYL 可将其转化，还能修饰蛋白质。这有助于深入理解细胞代谢与蛋白质功能调控机制。 巴豆酰辅酶 A（Crotonyl-CoA）是辅酶 A（CoA）的一 ...

Mitochondrial-supported bioenergetics decline and oxidative stress increases during aging. To address whether the dietary addition of acetyl-L-carnitine [ALCAR, 1.5% (wt/vol) in the drinking water] ...