The sarcoplasmic reticulum (SR) is a specialised organelle in skeletal muscle fibres that plays a pivotal role in regulating calcium dynamics crucial for muscle contraction and relaxation. Acting as ...

- Muscle cells, also known as myocytes, are specialized cells designed for contraction and force production. Skeletal Muscle Cells: These cells are long, cylindrical, and have a striated (or striped) ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...