“It’s genuinely surprising that the add-on gives vancomycin any ability at all to hit gram negatives,” says Kim Lewis, an ...

Gram-negative bacteria, notorious for their intrinsic and acquired resistance mechanisms, pose a significant threat to public health. The emergence of ...

Antimicrobial resistance has become one of the greatest threats to public health, with rising resistance to carbapenems being a particular concern due to the lack of effective and safe alternative ...

A massive treatment gap is leaving millions vulnerable to untreatable infections in low- and middle-income countries, as new data shows a dire shortfall in access to life-saving antibiotics. Study: ...

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut ...

The UK turns to artificial intelligence (AI) to reverse the rising numbers of infections that shrug off antibiotics.

A team led by Paul Hergenrother at the University of Illinois Urbana-Champaign has discovered a new antibiotic that exclusively targets gram-negative bacteria and avoids wiping out the ecosystem of ...

Expert Rev Anti Infect Ther. 2010;8(8):879-885. We recommend a thorough evaluation of patients with non-HACEK Gram-negative endocarditis to assess the necessity of surgical intervention. Decision to ...

• Require X (hemin) and/or V (nicotinamide adenine dinucleotide) factors for growth • Responsible for 0.5–1% of all cases of IE • Haemophilus aphrophilus is the most common species responsible for IE ...

A mineral-hogging fungus can “bully” bacteria into becoming more antibiotic resistant, according to new work published June 20 in the journal PLOS Biology by Fred Hutch Cancer Center scientists. The ...