Inspired by hepatic lobules, a novel artificial liver was developed by assembling morphological cell sheets with high accuracy in terms of cell type, density, and distribution. By simulating the ...

Organoids are miniature organs made up of different cell types that exhibit similar structures and functions to real organs. Organoids more closely reflect human physiological and pathological ...

The paper S. Hoehme et al., “Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration,” PNAS, 107:10371-76, 2010. Free ...

The liver is the only solid organ that uses regenerative mechanisms to ensure that the liver-to-bodyweight ratio is always at 100% of what is required for body homeostasis. When the liver is injured ...

While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery. Now, research from the ...

Scientists at the École polytechnique fédérale de Lausanne (EPFL), Switzerland, and the Weizmann Institute of Science, Israel, have uncovered that the expression of many liver genes is dually ...