苏州大学的实验人员在上述论文中发现Nicotinamide ribose（烟酰胺核糖）可在大鼠心肌缺血再灌注（I/R）损伤模型中起到保护作用，并且利用AbMole提供的SIRT3抑制剂3-TYP（CAS ...

Researchers outline why organs from older donors are often discarded and identify the biological and immunological pathways ...

缺血性脑卒中是全球主要的致死和致残原因，而在通过溶栓或取栓恢复血流的过程中，常会引发脑缺血再灌注损伤，加重神经损害。因此，寻找能干预该过程的新靶点至关重要。近年来，一种称为“铁死亡”的铁依赖性脂质过氧化细胞死亡方式被证实参与再灌注损伤，其中花生四烯酸 ...

GPR30 in brain microvasculature responds to bicarbonate, and its deficiency protects against ischemia-reperfusion injury, reducing neurological deficits and blood-brain barrier disruption. These ...

Alternative model systems to study ischemia-reperfusion are needed to support a wide range of disease-related investigations in the life sciences. Ischemia and reperfusion are relevant to many disease ...

Southwest Research Institute (SwRI) and Trinity University will improve a prodrug, a compound activated in the body, to ...

Inflammation plays a critical role in the development and progression of neurovascular disorders and stroke, impacting both acute and chronic phases of ...

Skin wounds from ischemia-reperfusion injuries -- tissue damage caused by blood returning to tissues after a period of oxygen deprivation -- may not heal appropriately in some patients, owing to ...

When an artery becomes blocked in a heart attack, the process of restoring healthy blood flow to the heart is called reperfusion. It usually involves a combination of medications to break down a blood ...