The goal of the study is to investigate host genetic and immunologic predictors of resistance to M. tuberculosis infection and progression from latent M. tuberculosis infection to active tuberculosis ...

CHAPEL HILL -- New research led by a University of North Carolina at Chapel Hill scientist shows for the first time how Mycobacterium tuberculosis, the germ responsible for TB, uses a system for ...

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune ...

Iron assimilation, storage and utilization is essential for M. tuberculosis pathogenesis and also involved in emergence of multi- and extensively-drug resistant strains. Heme is the preferable iron ...

New observations of the early stages of tuberculosis infection may turn scientists' understanding of the bug's pathogenesis on its head: clumps of immune cells, called granulomas, long thought to ...

lasma metabolomic analysis in active tuberculosis patients and healthy controls. Cerebral tuberculosis (CTB), a severe and often fatal form of central nervous system (CNS) tuberculosis, poses ...

Psychiatry has struggled to enter the precision medicine era. But through a mix of innovations and bootstrapping, progress is coming to the field. Scientists are ...