G protein-gated inwardly rectifying potassium (GIRK) channels are critical regulators of neuronal excitability and can be directly activated by ethanol. Constitutive deletion of the GIRK3 subunit has ...

Dopamine function and reward processing are highly interrelated and involve common brain regions afferent to the nucleus accumbens, within the mesolimbic pathway. Although dopamine function and reward ...

This is a preview. Log in through your library . Abstract Mice experiencing repeated aggression develop a long-lasting aversion to social contact, which can be normalized by chronic, but not acute, ...

Social rank regulates methamphetamine-seeking behavior by modulating the mesocortical and mesolimbic dopamine pathways, and winning experiences can remodel these circuits to suppress drug-seeking. In ...

Could coffee help to counteract some of the effects of alcohol on the brain, and potentially limit the risk of addiction? That's what's suggested by a new study of how caffeine interacts with the ...

Anorexia nervosa is a serious mental disorder that manifests with an intense fear of weight gain and a disturbed body image. This can lead to severe diet restrictions or other behaviors like purging, ...

Please provide your email address to receive an email when new articles are posted on . Structural and functional circuit deficits in the mesolimbic reward pathway contributed to measures of social ...

Drug addiction poses a global public health challenge, with limited therapeutic options and modest efficacy. While numerous studies have shown that social status profoundly impacts mental health and ...

ADHD is the most common neurobiological disorder in children. The key word being neurobiological. When in the throes of raising a neurodivergent child, it’s easy to forget that their behavior is ...