Primary mediastinal B-cell lymphoma (PMBL) is an aggressive extranodal B-cell non-Hodgkin's lymphoma with specific clinical, histopathological and genomic features. To characterize further the ...

If you have primary mediastinal B-cell lymphoma (PMBL), you’ve likely heard about CAR T gene therapy. There’s good reason for that. Loretta Nastoupil, MD, will tell you, “It’s just the most exciting ...

Diagnosis of PMBL using clinical and morphological features alone is imprecise, leading to an uncertain prognosis. Both research groups have devised a molecular signature to identify PMBLs and ...

Minimally Invasive Surgery for Early-Stage Cervical Carcinoma: Interpreting the Laparoscopic Approach to Cervical Cancer Trial Results The expansion cohort of the open-label, phase I/II CheckMate 436 ...

Even though it’s one of the latest and greatest cancer treatments, CAR T therapy still has its side effects. They’re often mild, but they can be serious and affect your heart, kidneys, and brain. That ...

This study looked at tissue samples and PET scans to learn more about ‘primary mediastinal diffuse large B cell lymphoma’ (PMBL) and the best way to treat it. Cancer Research UK supported this study.

Gene-expression profiling has been used to define 3 molecular subtypes of diffuse large B-cell lymphoma (DLBCL), termed germinal center B-cell-like (GCB) DLBCL ...