【导读】ITM2B是一种跨膜蛋白，经常发生裂解。ITM2B 的生理功能主要是在神经疾病背景下进行研究，但在癌症中的作用却很大程度上被忽视了。近日，厦门大学研究团队在期刊《Advanced Science》上发表了研究论文，题为“ITM2B ...

The global advanced renal cell carcinoma (RCC) market is experiencing rapid growth driven by innovative treatment approaches, rising disease awareness, and an expanding patient base. Key factors ...

Patients who have metastatic chromophobe renal cell carcinoma (ChrRCC) that harbors sarcomatoid features (SF) benefited from immunotherapy (IO)-containing regimens vs patients wit ...

恶病质不仅仅是体重的下降，更是肌肉和脂肪组织的非自愿性耗竭。在晚期癌症患者中，它像一个隐形的杀手，不仅严重降低生活质量，更直接导致了约20%的癌症相关死亡。对于肾透明细胞癌（ccRCC）而言，高达35%的患者会遭遇恶病质的折磨。长久以来，我们对于驱动 ...

XmAb819 demonstrated a manageable safety profile with primarily grade 1 or 2 cytokine release syndrome and no neurotoxicity in ccRCC patients. The trial involved 69 patients, with a 25% objective ...

这不仅是一个简单的数据差异，它暗示了一个深刻的生物学逻辑：HIF2 ...

A new study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas. The researchers' integrative analysis of comprehensive ...

Randomized Phase III Study of Amcenestrant Plus Palbociclib Versus Letrozole Plus Palbociclib in Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: ...

Renal cell carcinoma accounts for approximately 90% of kidney cancers, and current treatments fail to prevent metastasis in up to 40% of patients. Potentially effective is immunotherapy based on CAR T ...