Antifungal prophylaxis with azoles is considered standard in allogeneic hematopoietic SCT (allo-HSCT). Although sirolimus is being used increasingly for the prevention of GVHD, it is a substrate of ...

Please provide your email address to receive an email when new articles are posted on . One glass of grapefruit juice each day significantly slowed the body’s metabolism of sirolimus, suggesting ...

Efficacy of Low-Dose Interferon α2a 18 Versus 60 Months of Treatment in Patients With Primary Melanoma of ≥ 1.5 mm Tumor Thickness: Results of a Randomized Phase III DeCOG Trial Sarcomas are a ...

Switching heart transplantation patients from calcineurin inhibitor (CNI)-based to sirolimus-based immunosuppression was associated with an almost doubling of the malignancy-free survival rate in a ...

T-Cell–Replete HLA-Haploidentical Hematopoietic Transplantation for Hematologic Malignancies Using Post-Transplantation Cyclophosphamide Results in Outcomes Equivalent to Those of Contemporaneous ...

Boston, MA - A new study shows that substituting sirolimus for cyclosporine as immunosuppressive therapy in renal-transplant patients resulted in remission of proven Kaposi's sarcoma (KS) in these ...

Sirolimus, a drug typically used by transplant patients to prevent rejection, has been found in previous studies to have anti-cancer properties as well. While it’s not currently used to treat cancer, ...

A daily glass of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself, according to a new ...

CINCINNATI—Researchers at the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center have found that the FDA-approved drug sirolimus, used primarily to prevent rejection in ...

A glass a day of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself, according to a new ...