总之，这项研究首次系统性揭示GALNT2为一个由干扰素诱导、具有广谱抗病毒活性的关键效应分子，通过O-糖基化修饰病毒膜蛋白发挥抑制病毒感染入侵的全新机制。本研究不仅深化了对宿主-病毒相互作用的理解，也为开发针对新冠病毒、流感病毒等呼吸道病原的广谱抗病 ...

Respiratory viruses that have diverse strains and mutate rapidly, such as influenza and COVID-19, are difficult to block ...

A recent study in the journal PNAS from the lab of Julie Overbaugh reveals a previously unknown antiviral function of a gene involved in the immune defense against Zika virus that has implications for ...

Respiratory viruses that have diverse strains and mutate rapidly, such as influenza and COVID-19, are difficult to block ...

A new drug quashes all coronavirus variants. But regulatory hurdles and a lack of funding make it unlikely to reach the U.S. market anytime soon. By Benjamin Mueller Over the past year, America’s ...

Researchers have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by CAR T-cell immunotherapy. Researchers at ...

An experimental COVID-19 antiviral appears to be effective at preventing hospitalizations without some of the downsides of other treatments. A study appearing Wednesday in The New England Journal of ...

Interferon-Free Treatment: No Longer a Dream? Several studies were presented at both Digestive Disease Week (DDW) 2012 in May and at the European Association for the Study of the Liver (EASL) annual ...

Role of prophylactic regional lymph node radiation therapy on locoregional recurrence in Merkel cell carcinomas. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract ...