Have you ever wondered why endotoxin testing is crucial? Endotoxins are toxic substances found in the outer membrane of Gram-negative bacteria, and they can cause severe reactions in humans, including ...

Endotoxin refers to a component of the outer cell membrane of Gram-negative bacteria called lipopolysaccharide (LPS). LPS is the biologically active portion of naturally occurring endotoxin complexes.

With the introduction of pioneering technology for bacterial endotoxins testing (BET), it is critical to demonstrate equivalency across platforms. The Sievers Eclipse Ratio Verification Test was ...

Novel Approach to Achieving Consistent Results with the Limulus Amebocyte Lysate Test The standard tool for screening endotoxins—highly toxic, heat-stable lipopolysaccharides that constitute the outer ...

What are the benefits of microfluidic automation? Microfluidic automation is the most straightforward available form of automation for endotoxin testing on the market today. It streamlines endotoxin ...

The quality of water for pharmaceutical production (purified water, water for injection, and ultrapure water) is quantified and regulated through four parameters – total organic carbon (TOC), ...

New standards may help push more drugmakers to use a synthetic product for critical drug safety testing, instead of one made from horseshoe crab blood that has long drawn criticism. The U.S.

As thoroughly covered in your recent article (C&EN, Oct. 28, 2024, page 26), the issue of replacing the traditional natural product test for endotoxin, limulus amoebocyte lysate (LAL), with a ...

Every year in May when high tide coincides with the full moon, horseshoe crabs convene on the beaches of the mid-Atlantic coast to lay millions of eggs. At the same time, migratory shorebirds on their ...